产品货号:
Z15563
中文名称:
DPYD抗体
英文名称:
Anti-DPYD Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DPYD Antibody |
指标别名 | DHP;DHPDHASE;Dihydrothymine dehydrogenase;Dihydrouracil dehydrogenase;DPD;DPYD |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ELISA |
基因名称 | DPYD |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human DPYD. |
计算分子量 | 111KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | DPYD (Dihydropyrimidine Dehydrogenase),also called DPD,is an enzyme that in humans is encoded by the DPYD gene.The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism.The structure of the DPYD gene contains 23 exons spanning about 950kb.Using somatic cell hybrid strategies,the DPYD gene is mapped to the centromeric region of chromosome 1 between 1p22 and 1q21.By fluorescence in situ hybridization,the DPYD gene is mapped to 1p22.The highest level of DPD was found in monocytes followed by that in lymphocytes,granulocytes,and platelets,whereas no significant activity of DPD could be detected in erythrocytes.The activity of DPD in peripheral blood mononuclear cells was intermediate between that observed in monocytes and lymphocytes.By cDNA microarray,Western blot analysis,and luciferase reporter assay,the transcription factor LSF was identified as a positive regulator of DPYD. |
Uniprot ID | Q12882 |
基因名全称 | Dihydropyrimidine dehydrogenase [NADP(+)] |
蛋白名全称 | Dihydropyrimidine dehydrogenase [NADP(+)] |
推荐稀释比 | WB 1:500~1:2000 IHC-P 1:100~300 ELISA 1:20000 |
相关搜索:DPYD抗体,DPYD多抗,Anti-DPYD Antibody